Hand-foot-mouth disease (HFMD) is a common infectious disease caused by enterovirus infection, characterized by fever, sore throat, general malaise, rash or herpes on the hands, feet, and mouth. People are generally susceptible to enteroviruses and can be infected in different age groups, mainly in children under 5 years old. Some patients have fatal cardiopulmonary diseases and nervous system complications and may even lead to death.
The main enteroviruses that can cause HFMD include Coxsackievirus A (type 2, 4, 5, 6, 7, 9, 10, 16), Coxsackievirus B (type 1, 2, 3, 4, 5), enterovirus 71 and Echovirus. Among them, A16 and enterovirus 71 are the traditional high types, but A6 and A10 have gradually become the main pathogens causing HFMD in recent years.
The kit is used for qualitative detection of enterovirus universal (EVU, include A2, A4, A5, A6, A7, A9, A10, A12, A16, B1, B2, B3, B4, B5, enterovirus 71 and Echovirus, etc.) nucleic acid in human throat swab samples, and can distinguish enterovirus 71(EV71), Coxsackievirus A6(CA6), Coxsackievirus A10(CA10) and Coxsackievirus A16(CA16).