RNA safeguard is an aqueous, nontoxic, tissue storage reagent that rapidly permeates most tissues without frozen to stabilize and protect RNA in fresh specimens. Collect tissue and submerge into RNA safeguard reagent rapidly, which repress all kinds of factors that compromise RNA purity and integrality and destroy the integrality of cell structure. The specimen can simply be submerged in RNA safeguard and stored for analysis at a later date, avoid time-consuming labor of routine method.